Tuesday, December 29, 2009

Scientists discover antibody that kills prostate cancer

Scientists discover antibody that kills prostate cancer

By Agence France-Presse


US researchers have found an antibody that hunts down prostate cancer cells in mice and can destroy the killer disease even in an advanced stage, a study showed Monday.

The antibody, called F77, was found to bond more readily with cancerous prostate tissues and cells than with benign tissue and cells, and to promote the death of cancerous tissue, said the study published in the Proceedings of the National Academy of Science (PNAS)
When injected in mice, F77 bonded with tissue where prostate cancer was the primary cancer in almost all cases (97 percent) and in tissue cores where the cancer had metastasized around 85 percent of the time.

It recognized even androgen-independent cancer cells, present when prostate cancer is incurable, the study by researchers at the University of Pennsylvania showed.

F77 "initiated direct cell death of prostate cancer cells... and effectively prevented tumor outgrowth," it said.

But it did not target normal tissue, or tumor tissues in other parts of the body including the colon, kidney, cervix, pancreas, lung, skin or bladder, the study showed.

The antibody "shows promising potential for diagnosis and treatment of prostate cancer, especially for androgen-independent metastatic prostate cancer," which often spreads to the bones and is difficult to treat, the researchers wrote in PNAS.

Currently, the five-year survival rate for metastatic prostate cancer is just 34 percent, according to the study.

Prostate cancer is the second most common cancer among men, claiming half a million lives each year worldwide, according to the World Health Organization.


Thursday, December 24, 2009

Lost woman


A woman in a hot air balloon realized she was lost. She lowered
her altitude and spotted a man in a boat below. She shouted to him,

"Excuse me, can you help me? I promised a friend I would meet him
an hour ago, but I don't know where I am."

The man consulted his portable GPS and replied, "You're in a hot
air balloon, approximately 30 feet above ground elevation of 2,346 feet
above sea level. You are at 31 degrees, 14.97 minutes north latitude and
100 degrees, 49.09 minutes west longitude.

"She rolled her eyes and said, "You must be an Obama Democrat."

"I am,"replied the man. "How did you know?"

"Well," answered the balloonist, "everything you told me is
technically correct. But I have no idea what to do with your information,
and I'm still lost. Frankly, you've not been much help to me."

The man smiled and responded, "You must be a Republican."

"I am," replied the balloonist. "How did you know?"

"Well," said the man, "you don't know where you are or where you
are going. You've risen to where you are due to a large quantity of hot
air. You made a promise you have no idea how to keep, and you expect me to solve your problem.
You're in exactly the same position you were in
before we met, but somehow, now it's my fault."

Saturday, December 19, 2009

NJ veterans affairs official admits lies]